Dermal exposure assessment in occupational medicine

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Dermal exposure assessment in occupational medicine.

The importance of dermal exposure has increased during the last few years, mainly because of the reduction of respiratory exposure to toxicants. Pesticides, aromatic amines and polycyclic aromatic hydrocarbons are considered to be the chemicals at highest dermal risk. In the occupational exposure limit lists of the American Conference of Governmental Industrial Hygienists (ACGIH) and of many co...

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Carbofuran occupational dermal toxicity, exposure and risk assessment†

BACKGROUND Carbofuran is a carbamate insecticide that inhibits AChE. Although toxic by ingestion in mammals, it has low dermal toxicity, with relatively few confirmed worker illnesses. This risk assessment describes its time of onset, time to peak effect and time to recovery in rats using brain AChE inhibition in acute and 21 day dermal studies; in vitro rat/human relative dermal absorption for...

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on dermal exposure assessment

hazardous chemicals may enter the body by inhalation, ingestion, injection or dermal absorption. these exposure routes constitute the overall exposure burden on the body. most occupational exposure studies have focused on measurement of the concentration of air-borne contaminants and other possible routes of exposure are often overlooked. several studies have already highlighted the importance ...

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On dermal exposure assessment.

Hazardous chemicals may enter the body by inhalation, ingestion, injection or dermal absorption. These exposure routes constitute the overall exposure burden on the body. Most occupational exposure studies have focused on measurement of the concentration of air-borne contaminants and other possible routes of exposure are often overlooked.Several studies have already highlighted the importance o...

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Proposal for the assessment of quantitative dermal exposure limits in occupational environments: Part 1. Development of a concept to derive a quantitative dermal occupational exposure limit.

Dermal uptake of chemicals at the workplace may contribute considerably to the total internal exposure and so needs to be regulated. At present only qualitative warning signs--the "skin notations"--are available as instruments. An attempt was made to develop a quantitative dermal occupational exposure limit (DOEL) complementary to respiratory occupational exposure limits (OELs). The DOEL refers...

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ژورنال

عنوان ژورنال: Occupational Medicine

سال: 2002

ISSN: 0962-7480,1471-8405

DOI: 10.1093/occmed/52.3.151